By Nigel Arden, Francisco Blanco, C. Cooper, Ali Guermazi, Daichi Hayashi, David Hunter, M. Kassim Javaid, Francois Rannou, Frank Roemer, Jean-Yves Reginster
This Atlas offers an up to date and entire assessment of the historic and present views on osteoarthritis, together with the pathophysiology and epidemiology of the sickness. Written via top authors within the box of osteoarthritis, the booklet discusses type, etiology and possibility components for osteoarthritis, the sickness path and determinants of osteoarthritis development, medical positive aspects and analysis in addition to imaging how you can determine joint harm. The Atlas of Osteoarthritis concludes with the newest therapy updates together with either nonpharmacological and pharmacological remedies, in addition to surgical techniques for sufferers with the disorder. Osteoarthritis is the most typical kind of joint illness inflicting joint soreness, stiffness, and actual incapacity between adults. it truly is an enormous factor for either the person and society with its influence on public overall healthiness carrying on with to develop due to the getting older inhabitants, the emerging occurrence of weight problems, and the shortcoming of definitive remedies to avoid or halt the development of the disease.
Read or Download Atlas of Osteoarthritis PDF
Similar rheumatology books
Here's a compendium of information pertinent to the tools and protocols that experience contributed to either fresh advances in molecular drugs ordinarily in addition to to molecular foundation of rheumatic ailment particularly. This two-volume paintings collects the contributions of leaders within the box who disguise such interesting and leading edge themes as imaging and immunohistochemistry, research of cartilage and bone catabolism, immunobiology, and mobile trafficking.
Arthritis study: tools and Protocols, moment variation expands upon thefirst variation to give new and present suggestions for the examine of arthritis and similar stipulations. A compendium of leaders within the box give a contribution chapters that conceal sensible examine equipment comparable to the intravital multiphoton microscopy process, thoughts for comparing exhausted CD8 T telephone and for learning nucleic acid sensors and their results, tools for in vivo tetracycline-controlled transgenic mice and T cellphone receptor transgenic mice, protocols to realize V(D)J recombination items and microRNA, and the strategy to make bleomycin-induced dermal fibrosis.
This high-yield, simple handbook is a realistic street map for all physicians who diagnose and deal with sufferers with musculoskeletal signs, together with physiatrists, orthopedists, internists, kinfolk practitioners, rheumatologists, and neurologists. equipped via anatomic sector, the ebook offers a step by step method of the analysis and competitive nonsurgical administration of universal musculoskeletal signs.
- Diseases and disorders of mineral metabolism
- Immunological Aspects of Rheumatology
- ABC of common soft tissue disorders
- Pulmonary Hypertension (Contemporary Cardiology)
Extra resources for Atlas of Osteoarthritis
ADAMTS, a disintegrin and metalloproteinase with thrombospondin motifs; BMP, bone morphogenetic protein; CCL2, CC-chemokine ligand 2; CXCL13, CXC-chemokine ligand 13; EGF, endothelial growth factor; GM-CSF, granulocyte-macrophage colony-stimulating factor; IL, interleukin; IL-1Ra, IL-1 receptor antagonist; LIF, leukaemia inhibitory factor; LTB4, leukotriene B4; MMP, matrix metalloproteinase; NAMPT, nicotinamide phosphoribosyl transferase (also called visfatin); NGF, nerve growth factor; PGE2, prostaglandin E2; TIMP, tissue inhibitor of metalloproteinase; TNF, tumour necrosis factor; VCAM-1, vascular cell adhesion molecule 1; VEGF, vascular endothelial growth factor.
Cartilage degradation Under normal conditions, the physiologic homeostasis of the articular cartilage is driven by chondrocytes, which produce the structural matrix containing collagens (primarily collagen 39 Atlas of osteoarthritis Discovertebral osteoarthritis of the spine type II), and proteoglycans [6,13]. 5 Discovertebral osteoarthritis of the spine. Anteroposterior radiograph of the lower lumbar spine shows endplate-based sclerosis in the L4 lower and L5 upper end-plates with narrowing of the disc space between them (arrow).
Risk factors for incident radiographic knee osteoarthritis in the elderly: the Framingham study. Arthritis Rheum. 1997;40:728-733. 43 Spector T, Hart D, Doyle D. Incidence and progression of osteoarthritis in women with unilateral knee disease in the general population: the effect of obesity. Ann Rheum Dis. 1994;53:565-568. 44 Gelber A, Hochberg M, Mead L, Wang N, Wigley F, Klag M. Body mass index in young men and the risk of subsequent knee and hip osteoarthritis. Am J Med. 1999;107:542-548. 45 Cooper C, Snow S, McAlindon T, et al.
Atlas of Osteoarthritis by Nigel Arden, Francisco Blanco, C. Cooper, Ali Guermazi, Daichi Hayashi, David Hunter, M. Kassim Javaid, Francois Rannou, Frank Roemer, Jean-Yves Reginster