By Wettach G., Palmrose T., Morgan T.
The explicit path to USMLE Excellence in PathologyYou'll by no means locate a neater, extra effective, and extra targeted option to ace pathology and pathology-related questions about the USMLE than USMLE highway Map: Pathology. Designed to supply greatest studying in minimal time, this detailed evaluate deals a concise, inventive, and well-illustrated new method of studying pathology.Features
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Extra info for USMLE Road Map Pathology
4. The individual chromosomes are identiﬁed and categorized (morphologically) based on their staining characteristics and centromere placement (Figure 2–2). a. Acrocentric chromosomes have their centromere near one end of the chromosome and have satellite short arms encoding ribosomal RNA (rRNA). b. Metacentric chromosomes have a centrally placed centromere. 5. Chromosome studies are indicated for the following reasons: a. Cases of developmental delay b. Presence of dysmorphic features, neoplasia, or fertility issues c.
There are approximately 1400 reported mutations in the CFTR gene, which encodes a chloride channel that regulates secretion viscosity. 4. Most available genetic tests, for both prenatal diagnosis and carrier testing, consist of a panel of at least 25 of the most frequent mutations to identify nearly 90% of the cases. 5. Full CFTR gene sequencing or other mutation-scanning methods can be used to identify the remaining rare mutations. G. Hereditary Breast and Ovarian Cancer 1. Approximately 5–10% of breast cancers are associated with alterations in the breast cancer 1 and 2 (BRCA1 and BRCA2) genes.
B. Ear Canal 1.
USMLE Road Map Pathology by Wettach G., Palmrose T., Morgan T.